CyLH2Valley aims to develop and demonstrate a large-scale Hydrogen Valley in Castilla y León region, encompassing mobility, industry and energy applications. The project will guarantee at least two years of full operation aiming to achieve a full integration and operation during the period 2028-2029. The focus will be on operating the CyL Hydrogen Valley to demonstrate its financial viability, how all the different applications (9 pilots) fit together in an integrated system approach, and the versatility of hydrogen, as an energy vector, in enabling sector coupling. The financial viability of the CyL Hydrogen Valley will pave the way for the upscaling of the valley and the creation of a clean hydrogen economy in the CyL region by 2035, aligning the interests of the most relevant stakeholders from the hydrogen value chain. This contributes to the achievement of the EU hydrogen strategy and REPowerEU plan, while advancing towards the achievement of the 2030 Agenda for Sustainable Development.