The heaviest element which has been found in nature is uranium with 92 protons. So far, the elements up to atomic number 118 (oganesson) have been discovered in the laboratory. All transuranium elements are radioactive and their production rates decrease with increasing number of protons. An Island of Stability, where the nuclei have relatively long half-lives, is predicted at the neutron number 182 and, depending on the theoretical model, at the proton number 114, 120 or 126. Current experimental techniques do not allow to go so far to the neutron-rich side close to the Island of Stability. The observation of gravitational waves as well as electromagnetic waves originating from a neutron star merger has been published on October 16, 2017 and is a first proof of the nucleosynthesis of heavy elements in the r-process. It still remains an open question if superheavy nuclei have been formed in our universe. To answer these questions, we need insight into the nuclear properties of the heaviest elements and how these properties evolve when one moves toward to the neutron-rich side on the nuclear chart. In the NEXT project, I will set out to discover new, Neutron-rich, EXotic heavy nuclei using multi-nucleon Transfer reactions. I will measure their masses and, thus, pin down the ground state properties of these nuclei. These studies provide insight into the evolution of nuclear shells in the heavy element region. Furthermore, I will measure the fission half-lives of these isotopes. In order to realize the NEXT project, I will built a novel spectrometer, which is a combination of a solenoid separator and Multi-Reflection Time-of-Flight Mass Spectrometer. The broad experience in heavy element research and mass measurements that I have acquired over the years, and the unique infrastructure at my home institute that houses the AGOR accelerator, makes it so that I am ideally placed to start and lead the NEXT project.

Latent tuberculosis infection (TBI) occurs when someone is infected with Mycobacterium tuberculosis but does not have active TB disease. Those with TBI are at risk of developing active TB, with 8–10% progressing without antibiotic treatment, causing significant societal and economic impacts. Testing higher-risk groups, including immunocompromised individuals (e.g., those on immunosuppressive therapy, HIV-positive), close contacts with active TB cases, healthcare workers, and people from high TB prevalence countries (e.g., refugees), is crucial for TB control. The interferon-gamma release assay (IGRA) is a primary TBI test, detecting T cell immune responses to M. tuberculosis in blood. However, IGRA is technically challenging, requires long incubation times (24–48 hours), and incurs high costs (>100 EUR/test). These factors hinder the widespread screening of high-risk populations recommended by the WHO. We have developed a new technique, ProliSpot (patent pending), which detects antigen-specific T cell responses within several hours after collecting a blood sample and potentially overcomes the limitations of IGRA. This project's goal is to determine ProliSpot's in vitro diagnostic (IVD) potential for TBI testing. To achieve this, we will assess clinical feasibility by testing blood samples from TB patients and control subjects and compare the results with IGRA. Moreover, we will identify the subsequent steps needed for clinical development, particularly for the Investigational Medical Device Dossier (IMDD) and other requirements of the EU in vitro diagnostics regulations (IVDR). We will also perform pre-commercialization studies and define funding and networking strategies. Given that TBI testing is crucial for TB control, tens of thousands are screened annually in Europe, there is a societal need for increased TBI screening, and improved TBI testing methods are needed, the project's societal and economic impact is expected to be significant.

With feature sizes of integrated circuits rapidly approaching molecular length scales, historical motivations to pursue the use of individual molecules in electronic circuits can no longer be justified based on their size alone. Instead, the focus has shifted towards the identification and exploitation of unusual transport phenomena unique to molecular materials (dominated by quantum mechanics) which can complement or supplant current silicon-based technologies. With the large majority of previous studies centered around the study of organic, redox-inactive molecules - typically transporting charge via single-step tunnelling processes - investigations of analogous systems that explicitly involve multi-step tunnelling, or ‘hopping’, behaviour are comparatively rare. In this project I propose to systematically study hopping processes in molecular-scale electronics (HOPELEC), with two primary objectives: (i) to construct the first single-molecule current oscillator; and (ii) probe under-explored current rectification mechanisms for single-molecule diodes. This highly interdisciplinary research area will involve the synthesis of new multi-site redox-active metal complexes capable of binding between nanoscale electrodes. Transport through these systems will be studied both at the single-molecule level using the scanning tunnelling microscope-based break junction technique, and in large area measurements using the eutectic Ga−In method. This work will expose new molecular-scale device mechanisms at the intersection of Marcus and Landauer theories, and contribute to our understanding of related processes in biology and materials science. Project results will be actively promoted through Outreach workshops on electronics/computation (translated also to YouTube). The extensive training, enhanced international profile, networks, and new experiences provided by this Fellowship will function as a 'springboard' in propelling me from Ph.D. student to independent research scholar.

One of the most widespread social phenomena that we witness nowadays is the emergence of collective action movements in which low-status groups mobilize in order to trigger social change (e.g. Arab Spring, Indignados, the Occupy Movement). Interest in collective action has mushroomed in the last decade, as confirmed by the fact that from the 1602 hits found in Psycarticles using the “collective action” term, more than 70% of them date from 2000 or later. However, this research is almost exclusively focused on low-status groups without taking into account high-status groups’ reactions. Existing literature on high-status groups either puts the emphasis on individual psychological processes linked to prejudice reduction or on the reinforcement of status quo. Yet, the likelihood of social change and, ultimately, the unfolding of intergroup conflict cannot be understood without considering both low-status groups’ actions and high-status groups’ reactions. This project directly targets high-status groups’ role in social change. We analyze high-status groups’ support for normative (i.e., socially accepted protest such as demonstrations) vs. nonnormative collective action behaviors (i.e., radical protest such as the use of violence). This research project main goals are to examine: 1) psychological mechanisms explaining high-status groups’ support for normative and nonnormative collective action; 2) disentangle two theoretically contrasting perspectives by analyzing moderating conditions at different levels that lead to higher support from high-status groups in response to normative and nonnormative collective action. The main idea developed is that normative and nonnormative collective action will prove effective in eliciting high-status group support in different situations. In general, this will depend on a matching between the type of action and the individual (Question 1), the type of low-status demand (Question 2) and the socio-structural context (Question 3).