This European Fellowship project will benefit the researcher by giving and enhancing the knowledge and skills for a future generation of CPSs which enjoy the unique feature of context-active resilience. With such new capability and training, the researcher is expected to realise his potential and gain his leading role at international level in CPS research community. Context-active resilience is a novel concept of CPS resilience proposed in this action, which emphasises active and even proactive response to the dynamic state of CPS and its users in real-time. CAR Patterns will be identified via the empirical analysis of practical CPS systems, and specified with the developed Meta-Intelligence and populated into a semantic repository. Due to the wide and critical roles of CPS in industry and society and the novelty of context-active resilience, the proposal is both timely and significant. Acting as a bridge, the project will simultaneously advance the theoretic approach and art of practice of this emerging topic, improve the competency and career of the fellow, enhance and complement the host’s research profile and infrastructure, and benefit the society, living, economy and related research communities significantly.

Ensemble is an interactive suite of jewellery to be experienced by up to ten people within a gallery environment, which provides an alternative, ambigious style of interaction in wearable computing. It explores the issue of user control of personal information in social interactions, and highlights ways in which self-determination may take place through the medium of sound. Short narratives recorded by wearers are more or less masked by dynamic musical output, which in turn is determined by a number of factors taking place in the social interaction, including gestural, vocal and biometric. Furthermore, the functional element of the jewellery is approached as a design material, inevitably carrying expression just as the more common visual and tactile aspects do. Thus the contemporary crafts bsaed design process seeks to make use of the constraints and opportunities presented by the novel 'Speckled Computing' enabling interaction, in the same way that it seeks to create fresh expressions through those materials used at the workbench.

This project comes under the Challenged Ecosystems theme and undertakes a "catchment to coast" investigation of a river catchment which is impacted by multiple pollution sources. It includes the sub-theme of multiple stressors in the form of pollutants associated with antibiotic resistance (AR). These include antibiotic resistant bacteria (ARB), antibiotic resistant genes (ARG) and antibiotic resistance (AR) selective chemicals such as antibiotics, heavy metals and other chemicals of emerging concern (CECs). These stressors affect the evolution and spread of antibiotic resistance and have a direct impact as environmental pollutants. These direct environmental effects impact natural microbial populations, invertebrates and vertebrates within the river catchment area. Effects range from disrupting microbial communities, their evolution, diversity and ecosystem functions. In addition, these pollutants may be toxic to higher organisms with physiological effects, interfering with development and behaviour, and effects on the host microbiomes (Kraemer et al., 2019). The project also includes the sub-theme of societal well-being. The alarming rise in resistance to antibiotics is now widely accepted as being one of the most serious public health crises faced today. Part of the urgency of this crisis is that it is not new. The large number of AMR action plans agreed at national and international level since the early 1990s indicate this is a well known problem. Despite many successful interventions, especially lowered consumption in human and animals in developed countries, the level of resistance is still rising. This is recognised as a multi-sectoral issue, and is often framed within "The One Health model", which links the human, animal, and environment health domains. However, the environmental domain has been till very recently largely ignored. The significant contribution of the environment to AR was acknowledged by the WHO in 2016 and by the UK AMR strategy in 2019. As a result there is a critical lack of data for supporting mitigation or intervention strategies. If you consider how antibiotics now play a role in virtually every part of our health system: simple things like scratches could kill you, childbirth could kill you, cancer treatment, major surgeries, diabetes, in the background in all of these, is often the use of antibiotics," De Barro said. https://www.theguardian.com/world/2020/sep/10/superbugs-a-far-greater-risk-than-covid-in-pacific-scientist-warns Recent studies indicate that the environment is a significant contributor to the transmission and emergence of resistant pathogens (Singer et al., 2016) (Proia et al., 2018)(Graham et al., 2010). An overview of the three main roles of the external environment in antibiotic resistance development and dissemination has been proposed - (1) a transmission pathway for antibiotic resistant (AR) pathogens, (2) selection of enhancement of resistance and (3) emergence of novel resistance. The latter two are mediated by environmental AR selective chemicals such as antibiotics, heavy metals and other chemicals of emerging concern (CECs). (J Bengtsson-Palme et al., 2018) The River Almond catchment area has all the ingredients of an AR transmission and selection "hotspot". Including nine waste-water treatment plants (WTTP), numerous combined sewer overflows (CSO) and septic tanks, farm animal waste, mining discharge and landfill sites. This project will provide baseline data on the levels and sources of antibiotic resistance (ARB and ARG) and AR selective chemicals in the River Almond catchment area. Aim To determine the abundance of antibiotic resistance (ARB and ARG) and investigate the correlation with antibiotic resistance selective chemicals along a river impacted by multiple pollution sources in order to provide a baseline for future risk assessment and intervention strategies.

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.