In FuturEnzyme, a multi-disciplinary and multi-actor consortium of 16 leading academic and industrial partners will develop technologies of the FUTURe for low-cost ENZYMEs for environment-friendly products. The consortium will develop the most advanced innovative solutions in a fast-track to market platform to discover, design, optimise and formulate enzymes. The high-tech enzyme development platform will use big biodata mining of both public and internal databases and bio-resources, and disruptive machine learning, activity-based bioprospecting, protein engineering, nano-biotechnology, upscale fermentation, and downstream processing systems. The enzymes developed will be used to develop economically viable products on 3 market segments, textiles, detergents, and cosmetics, which combine a higher level of functionality with greater sustainability during their production, use or end-of-life: they respond to consumer and industry requests for greener products. We will also bring to fruition the enormous potential of the developed enzymes for use as catalysts to faster yield greener, more valuable, and sustainable products in other market sectors. The strong collaboration of the academic and industry partners will be supported by clusters, thus making sure we take a holistic approach. Analysing technology, market, consumer, and socio-economic demands, and assessing safety, risk, and life-cycle analysis during the technology and product development in an iterative process, will ensure the results will be effective and relevant. They also contribute to the goals of ensuring innovation capacity and economic success, while reducing the environmental impacts of consumer products. The consortium will interact with a broad stakeholder network to ensure uptake of its developments and feedback insights towards policy-makers.

INMARE stands for “Industrial Applications of Marine Enzymes: Innovative screening and expression platforms to discover and use the functional protein diversity from the sea”. It is a collaborative Innovation Action to streamline the pathways of discovery and industrial applications of new marine enzymes and bioactives for targeted production of fine chemicals, drugs and in environmental clean-up applications. The INMARE consortium will unify the multidisciplinary expertise and facilities of academic and industry partners. This will include integrating the following core activities: advanced technologies to access and sample unique marine biodiversity hot-spots; state-of-the art technologies for construction of metagenomic libraries; innovative enzyme screening assays and platforms; cutting-edge sequence annotation pipelines and bioinformatics resources; high-end activity screening technology; bioanalytical and bioprocess engineering facilities and expertise, nanoparticle-biocatalysts; high-quality protein crystallization and structural analysis facilities and experts in IP management for biotechnology. The companies involved in the project are market leaders in enzyme production and biocatalysis processes designed to efficiently deliver safer (pharmaceuticals) cheaper (agriculture) and biobased (biopolymers) products. They also have impressive track record in environmental clean-up technologies and are committed to promoting public understanding, awareness and dissemination of scientific research. The main emphasis will be focused on streamlining and shortening the pipelines for enzyme and ‘bioactive compound’ discovery towards industrial applications through the establishing of marine enzyme collections with a high proportion of enzymes-“allrounders”. The project will also prioritize the identification of novel lead products and the delivery of improved prototypes for new biocatalytic processes.