To meet the global and European challenges of reducing the GHG emissions from the construction sector, Build-in-Wood will develop a sustainable and innovative wood value chain for the construction of multi-storey wood buildings. The potential estimated impact from Build-in-Wood is a reduction of GHG emissions of 12.1 MT/year by 2030. Build-in-Wood will, based on experiences from the stakeholders involved in construction of some of the worlds largest wooden multi-storey buildings, take building with wood beyond state of the art. The consortium has identified a strong need for improving the whole value chain and intent to make wood a competitive building material by delivering a fully documented, demonstrated, sustainable and cost effective building system. Build-in-Wood will address this challenge by innovative development of materials and components as well as structural systems and façade elements for multi-storey wood buildings fit for both new construction and retrofitting. Developments will be delivered by means of a dynamic co-created web-based building configurator – the Design Guide – and a complimentary web-based toolbox of documented materials and components. Build-in-Wood will demonstrate full-scale digital case projects for real projects and test system prototypes in operational environments. Active engagement of cities and their building ecosystems through technical and thematic co-creation workshops will strengthen the urban-rural connections. All developed materials, components and system prototypes will be tested, piloted and fully documented for immediate market uptake. Based on developments, recommendations for new or updated European harmonised technical specifications and Eurocodes will be provided. To meet consumer acceptance, regulatory and sustainability requirements, Build-in-Wood includes life-cycle, socio-economic and safety assessments that will guide policy and decision-making at industry and EU level.