In today's dynamic industrial landscape, the agility of workers to embrace change stands as a critical factor. The competitive edge of industries heavily relies on the adeptness, innovation, and adaptability of their workforce. Identified skill gaps and mismatches between labor demand and supply pose direct hindrances to the creation of employment opportunities. It is imperative that skill development aligns with the evolving socio-economic dynamics. Education and training must be tailored to equip individuals with the requisite skills to navigate and excel in the field of green-digital technologies. The Hungarian presidency conference will address different aspects of skills development and the smart specialization concept through various program formats and networking activities, involving EU-level and national policymakers, researchers and training experts. The conference will contribute to developing the conceptual framework of skills development for smart specialisation, address differences between member states and provide evidence for better integration of skills development into S3 strategies.