The LUMEN project is a groundbreaking initiative aimed at revolutionizing cross-domain collaboration and discovery processes in the fields of Mathematics (Maths), Social Sciences and Humanities (SSH), Earth System (ES), and Molecular Dynamics (MD), and beyond. Leveraging the successful GoTriple platform, renowned for its service to the SSH community, LUMEN seeks to extend its functionality to foster interoperability across scientific domains. Through interdisciplinary solutions spanning all four domains, LUMEN will redefine the process of discovery with radical innovations, simplifying initial research phases and facilitating access to advanced AI-powered tools for researchers. By expanding existing discovery platforms in the SSH and Maths domains and developing new platforms for other domains, LUMEN aims to fundamentally transform EOSC services, promoting innovative and customizable solutions for data discovery, attracting new users, and fostering Open Science principles. The project will also drive multidisciplinary cooperation through collaborative platforms and onboard new scientific communities into EOSC, providing them with the necessary tools. Ultimately, LUMEN seeks to revolutionize how research outputs are created, shared, and utilized across scientific domains, enhancing scientific discoveries, fostering interdisciplinary collaboration, and promoting innovation and trust in European scientific research.