With Portugal holding the Presidency of the EU Council during the first semester of 2021, it provides an excellent opportunity to strengthen and promote the main EC priorities, including the European Green Deal and A Europe fit for the digital age. The "All-Atlantic R&I for a Sustainable Ocean: High-level & Stakeholders Conference" contributes to the implementation of these priorities based on strengthening R&I Cooperation across and along the Atlantic Ocean, from “pole to pole”. This conference will bring together high-level representatives and marine R&I stakeholders, from along and across the Atlantic Ocean, in a dialogue that will contribute to enhancing the science diplomacy efforts that began in 2011 at the European level, with the launching of the Atlantic Strategy and its 1st. Action Plan (2013) and the signing of the Galway and Belém Statements (respectively in 2013 and 2017). The event will be a step forward in the All-Atlantic Cooperation; it will be the opportunity to discuss the progress made so far, endorse a vision for the next years and launch a Pledging Platform as a new approach to the existing cooperation. This Platform will provide an understanding of the Atlantic marine R&I cooperation, enhancing stakeholder participation to co-design future actions and to monitor the progress enlarging the cooperative efforts. Discussions on the need for upscaled cooperation and new methodologies for ocean observation linked to digitalization processes represent an important innovative look forward to the integration of the Ocean-Space-Climate Nexus contributing to the topic of Ocean Sustainability. The conference’s Ministerial dimension linked to the stakeholders dynamic participation and side events will ensure the adequate involvement of the “All-Atlantic'' States and players and contributing to taking this All-Atlantic R&I Cooperation by two main legacy outputs, the Azores PPEU Conference Declaration and the All-Atlantic Pledging Platform.