Abstract: 5G-DIVE targets end-to-end 5G trials aimed at proving the technical merits and business value proposition of 5G technologies in two vertical pilots, namely (i) Industry 4.0 and (ii) Autonomous Drone Scout. These trials will put in action a bespoke end-to-end 5G design tailored to the requirements of the applications targeted in each vertical pilot, such as digital twinning and drone fleet navigation applications. 5G-DIVE’s bespoke design is built around two main pillars, namely (1) end-to-end 5G connectivity including 5G New Radio, Crosshaul transport and 5G Core, and (2) distributed edge and fog computing integrating intelligence located closely to the user. The latter pillar extends significantly beyond the EU- TW-Phase-I 5G-CORAL solution framework by adding support for automation based on artificial intelligence and distributed ledger technologies. The targeted intelligent tailored design is envisioned to achieve optimized performance and thus boost significantly the business value proposition of 5G in each targeted vertical application. 5G-DIVE trials target pilots running for several weeks on the premises of the vertical applications in real-life testbeds in Europe and Taiwan, leveraging noticeably the European 5G end- to-end facilities from ICT-17 call and Taiwan’s testbed facilities.